一种著名的钾通道在溶酶体中起着关键作用。
A well-known potassium channel plays a critical role in lysosomes.
作者信息
Zhu Michael X
机构信息
Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
出版信息
J Cell Biol. 2017 Jun 5;216(6):1513-1515. doi: 10.1083/jcb.201704017. Epub 2017 May 16.
Abstract
Whole-endolysosome patch clamping presents new opportunities to identify and characterize channels pivotal for these acidic organelles. In this issue (Wang et al., 2017. https://doi.org/10.1083/jcb.201612123), the identification of a role for the large conductance calcium-activated potassium channel brings new thinking about regulation of lysosome membrane potential and function.
摘要
全内溶酶体膜片钳技术为鉴定和表征这些酸性细胞器的关键通道提供了新机会。在本期（Wang等人，2017年。https://doi.org/10.1083/jcb.201612123）中，大电导钙激活钾通道作用的鉴定为溶酶体膜电位和功能的调节带来了新的思考。
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