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库欣综合征、皮质醇与认知能力:一例报告

Cushing's Syndrome, Cortisol, and Cognitive Competency: A Case Report.

作者信息

Oronsky Neil, Thilagar Bennett, Ray Carolyn M, Caroen Scott, Lybeck Michelle M C, Ferry Lindsey, Voves Ronald A, Oronsky Bryan

机构信息

aCFLS, San Jose, CA, USA.

bEpicentRx, Inc., San Diego, CA, USA.

出版信息

Case Rep Oncol. 2017 Apr 6;10(1):325-327. doi: 10.1159/000470833. eCollection 2017 Jan-Apr.

DOI:10.1159/000470833
PMID:28512418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5422746/
Abstract

Glucocorticoids are associated with immunosuppression and neuropsychiatric complications. We describe the case of a carcinoid patient with Cushing's syndrome (CS) and neurocognitive impairment due to ectopic ACTH production who developed sepsis and died because of his family's decision to withdraw antibiotic treatment. This report is presented to illustrate the importance of advanced-care planning in patients with CS.

摘要

糖皮质激素与免疫抑制及神经精神并发症有关。我们描述了一例类癌患者,其患有库欣综合征(CS),因异位促肾上腺皮质激素分泌导致神经认知障碍,该患者发生了败血症,最终因家属决定停止抗生素治疗而死亡。本报告旨在说明CS患者进行临终关怀规划的重要性。

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1
Cushing's Syndrome, Cortisol, and Cognitive Competency: A Case Report.库欣综合征、皮质醇与认知能力:一例报告
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[The ectopic ACTH syndrome].[异位促肾上腺皮质激素综合征]
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本文引用的文献

1
Neuropsychiatric disorders in Cushing's syndrome.库欣综合征中的神经精神障碍。
Front Neurosci. 2015 Apr 20;9:129. doi: 10.3389/fnins.2015.00129. eCollection 2015.
2
Advance directives in an oncologic intensive care unit: a contemporary analysis of their frequency, type, and impact.肿瘤重症监护病房中的预先指示:对其频率、类型和影响的当代分析。
J Palliat Med. 2011 Apr;14(4):483-9. doi: 10.1089/jpm.2010.0397. Epub 2011 Mar 18.
3
Cushing's syndrome complicated by multiple opportunistic infections.库欣综合征并发多种机会性感染。
J Endocrinol Invest. 1998 May;21(5):329-33. doi: 10.1007/BF03350337.
4
Differential diagnosis and management of Cushing's syndrome.库欣综合征的鉴别诊断与管理
Annu Rev Med. 1996;47:443-61. doi: 10.1146/annurev.med.47.1.443.