J Phys Act Health. 2017 Sep;14(9):716-725. doi: 10.1123/jpah.2016-0595. Epub 2017 May 17.
Although the relationship between physical activity and arterial stiffness has been shown in healthy persons, it remains controversial in obese persons.
From January 2014 to September 2014, we evaluated 795 obese subjects from 25 public health centers in Seoul, Korea. We compared physical activity and brachial-ankle pulse wave velocity (baPWV) between obese subjects with metabolic syndrome (MetS) (MO) and obese subjects without MetS (NMO).
The MO group had more men, higher body mass index (BMI), higher fasting glucose level, lower high-density lipoprotein-cholesterol level, and higher triglyceride level. The mean physical activity levels were similar between the 2 groups. baPWV was higher in the MO group than the NMO group. MO group showed positive correlation between baPWV and physical activity (P = 0.04). Interestingly, baPWV was significantly higher in the MO group than in the NMO group in subjects with moderate and vigorous physical activity (1403.4 cm/sec vs 1349 cm/sec [95% CI 21.4 to 87.4], P < .05). Multivariate regression analysis demonstrated that brachial-ankle pulse wave velocity was apparently associated with age, BMI, blood pressure, and glucose level.
In a community-based population, baPWV was higher in obese MetS group compared with obese non-MetS group. Physical activity showed different association with baPWV depending on metabolic status.
尽管身体活动与动脉僵硬之间的关系在健康人群中已经得到证实，但在肥胖人群中仍存在争议。
2014 年 1 月至 2014 年 9 月，我们评估了来自韩国首尔 25 个公共卫生中心的 795 名肥胖患者。我们比较了患有代谢综合征（MO）和无代谢综合征（NMO）的肥胖患者之间的身体活动和肱踝脉搏波速度（baPWV）。
MO 组男性更多，体重指数（BMI）更高，空腹血糖水平更高，高密度脂蛋白胆固醇水平更低，甘油三酯水平更高。两组之间的平均身体活动水平相似。 MO 组的 baPWV 高于 NMO 组。 MO 组的 baPWV 与身体活动呈正相关（P = 0.04）。有趣的是，在有适度和剧烈身体活动的 MO 组中，baPWV 明显高于 NMO 组（1403.4 cm/sec 比 1349 cm/sec [95%CI 21.4 至 87.4]，P <.05）。多元回归分析表明，baPWV 与年龄、BMI、血压和血糖水平明显相关。
在基于社区的人群中，肥胖代谢综合征组的 baPWV 高于肥胖非代谢综合征组。身体活动与 baPWV 的关系因代谢状态而异。
