Emmerich Ilka Ute
Dr. Ilka Ute Emmerich, VETIDATA, Institut für Pharmakologie, Pharmazie und Toxikologie, Veterinärmedizinische Fakultät, Universität Leipzig, An den Tierkliniken 39, 04103 Leipzig, E-Mail:
Tierarztl Prax Ausg G Grosstiere Nutztiere. 2017 Jun 20;45(3):176-181. doi: 10.15653/TPG-170267. Epub 2017 May 17.
In 2016, only one newly developed active pharmaceutical ingredient for horses and food-producing animals was released on the German market for veterinary drug products. The immunomodulator Pegbovigrastim is now available as an injection solution for cattle (Imrestor). Four established veterinary active pharmaceutical ingredients are available for further species: the ectoparasitic Amitraz (Apitraz) from the triazapentadiene group was additionally authorized for honeybees, the expectorant Bromhexine (Exflow Vet) for chickens, turkeys and ducks and the macrolide antibiotic Gamithromycin (Zactran) for pigs. The dopamine D receptor agonist Cabergolin (Velactis) was released for dairy cattle. However, the authorization was suspended a few months after market introduction because of severe side effects. Additionally, one veterinary drug with a new combination of active ingredients as well as one active substance in mono-preparation have been launched on the market for horses and food producing animals.
2016年，德国市场上仅有一种新开发的用于马匹和食用动物的活性药物成分投放用于兽药产品。免疫调节剂培戈维司亭现在有用于牛的注射溶液（Imrestor）。有四种已确立的兽用活性药物成分可供用于其他物种：来自三氮杂戊二烯类的外寄生虫驱避剂双甲脒（Apitraz）额外被批准用于蜜蜂，祛痰药溴己新（Exflow Vet）用于鸡、火鸡和鸭，大环内酯类抗生素加米霉素（Zactran）用于猪。多巴胺D受体激动剂卡麦角林（Velactis）投放用于奶牛。然而，由于严重的副作用，该产品在上市几个月后授权被暂停。此外，一种具有新活性成分组合的兽药以及一种单一制剂中的活性物质已投放于马匹和食用动物市场。
