Moris Dimitrios, Tsilimigras Diamantis I, Chakedis Jeffery, Beal Eliza W, Felekouras Evangelos, Vernadakis Spiridon, Schizas Dimitrios, Fung John J, Pawlik Timothy M
Department of Surgery, Division of Surgical Oncology, The Ohio State University Wexner Medical Center and James Cancer Hospital and Solove Research Institute, Columbus, Ohio.
First Department of Surgery, Laikon General Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
J Surg Oncol. 2017 Sep;116(3):288-297. doi: 10.1002/jso.24671. Epub 2017 May 17.
The use of liver transplantation (LT) for liver metastases attempted in the early 1990's was associated with poor perioperative outcomes and unacceptably low overall survival. Recently, there has been renewed interest in LT as a treatment option for colorectal liver metastases (CLM) in countries where organ supply is high. To date, no meticulous analysis about the efficacy, safety and outcomes of LT in CLM patients has been published. We present the first systematic review on the subject.
20世纪90年代初尝试将肝移植（LT）用于治疗肝转移瘤，其围手术期结果不佳，总体生存率低得令人难以接受。最近，在器官供应充足的国家，人们对将肝移植作为结直肠癌肝转移（CLM）的一种治疗选择重新产生了兴趣。迄今为止，尚未发表关于肝移植治疗CLM患者的疗效、安全性和结果的详尽分析。我们给出了关于该主题的首篇系统综述。
