Laboratory for Air Pollution and Environmental Technology, Swiss Federal Laboratories for Materials Science and Technology (Empa) , 8600 Dübendorf, Switzerland.
Department of Physics and Technology, UiT-The Arctic University of Norway , 9019 Tromsø, Norway.
Anal Chem. 2017 Jun 20;89(12):6377-6383. doi: 10.1021/acs.analchem.6b04511. Epub 2017 May 26.
A broadly tunable mid-infrared vertical-external-cavity surface-emitting laser (VECSEL) is employed in a direct absorption laser spectroscopic setup to measure breath acetone. The large wavelength coverage of more than 30 cm at 3.38 μm allows, in addition to acetone, the simultaneous measurement of isoprene, ethanol, methanol, methane, and water. Despite the severe spectral interferences from water and alcohols, an unambiguous determination of acetone is demonstrated with a precision of 13 ppbv that is achieved after 5 min averaging at typical breath mean acetone levels in synthetic gas samples mimicking human breath.
一种宽调谐中红外垂直外腔面发射激光器（VECSEL）被应用于直接吸收激光光谱学装置中，以测量呼吸中的丙酮。3.38μm 处超过 30cm 的大波长覆盖范围除了可以测量丙酮外，还可以同时测量异戊二烯、乙醇、甲醇、甲烷和水。尽管水和醇类存在严重的光谱干扰，但在经过 5 分钟的平均后，仍能以 13ppbv 的精度明确地确定丙酮，这一精度是在模拟人类呼吸的合成气样本中典型的呼吸平均丙酮水平下实现的。
