伊曲康唑对真菌萌发的活性。
Itraconazole activity against fungal germination.
作者信息
Strippoli V, Simonetti N, Retico A, Lucchetti G
机构信息
Institute of Microbiology, University of Rome La Sapienza, Italy.
出版信息
Drugs Exp Clin Res. 1988;14(5):341-5.
PMID:2851427
Abstract
Itraconazole was found to be superior to ketoconazole in its antifungal activity in vitro against Hyphomycetes and Candida. In particular, complete inhibition of germination of Candida albicans and Aspergillus spp. by a lower dose of itraconazole can explain the better activity in vivo of this drug.
摘要
体外研究发现，伊曲康唑对丝状真菌和念珠菌的抗真菌活性优于酮康唑。特别是，较低剂量的伊曲康唑就能完全抑制白色念珠菌和曲霉菌属的孢子萌发，这可以解释该药物在体内具有更好的活性。
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