Vladimirova T Yu, Barishevskaya L A, Lyamin A V, Kondratenko O V, Velikanov A K
Samara State Medical University, Samara, Russia, 443099.
Meditsina LLC, Samara, Russia, 443124.
Vestn Otorinolaringol. 2017;82(2):55-59. doi: 10.17116/otorino201782255-59.
The purpose of the present study was to evaluate the effectiveness of nitrofuranes applied for the treatment of chronic tonsillitis. A total of 92 subjects divided into three cohorts were involved in this study. Cohort 1 included 43 patients presenting with decompensated chronic tonsillitis and having pathogens in palatine tonsil lacunae. Cohort 2 was comprised of 13 patients with compensated chronic tonsillitis having pathogenic microflora of the same localization, while Cohort 3 was composed of 36 patients resembling those of cohort 1 in terms of clinical presentation, pathogen composition, and microbial spectrum. While the patients of cohort 1 and cohort 2 were treated by rinsing their tonsil lacunae with a furasol solution as a single-drug therapeutic procedure, those comprising Cohort 3 underwent treatment with furacilinum for the same purpose. The results of the study give evidence of the important advantages of furasol therapy over other modalities for the conservative treatment of chronic tonsillitis.
本研究的目的是评估硝基呋喃类药物用于治疗慢性扁桃体炎的有效性。本研究共纳入92名受试者,分为三个队列。队列1包括43例失代偿性慢性扁桃体炎患者,其腭扁桃体隐窝中有病原体。队列2由13例代偿性慢性扁桃体炎患者组成,这些患者相同部位有致病微生物群落,而队列3由36例患者组成,这些患者在临床表现、病原体组成和微生物谱方面与队列l相似。队列1和队列2的患者采用呋索溶液冲洗扁桃体隐窝作为单一药物治疗方法,而队列3的患者采用呋喃西林进行相同目的的治疗。研究结果证明了呋索疗法相对于其他慢性扁桃体炎保守治疗方式的重要优势。