Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.
Immunity. 2017 May 16;46(5):773-775. doi: 10.1016/j.immuni.2017.04.015.
Normalization of tumor blood vessels enhances the infiltration and functions of T cells. Tian et al. (2017) report that effector CD4 T cells, in turn, support vascular normalization, highlighting intertwined roles for blood vessels and T cells in cancer.
肿瘤血管正常化可增强 T 细胞的浸润和功能。Tian 等人(2017 年)报告称,效应性 CD4 T 细胞反过来又支持血管正常化,这突出了血管和 T 细胞在癌症中的相互作用。