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以多动和双相情感障碍为表现且伴有罕见药物不良反应的脑白质营养不良

Leukodystrophy Presenting as Hyperactivity and Bipolarity with Uncommon Adverse Drug Reaction.

作者信息

Sutar Roshan, Ray Anirban, Sheshadri Shekhar P

机构信息

Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Department of Child and Adolescent Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

出版信息

Indian J Psychol Med. 2017 Mar-Apr;39(2):202-204. doi: 10.4103/0253-7176.203115.

DOI:10.4103/0253-7176.203115
PMID:28515562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5385754/
Abstract

Leukodystrophy is a group of demyelinating neurodegenerative diseases of brain with varied presentation and multiple etiologies. Prognosis is predominantly dismal. Misdiagnosis and wrong treatment are common in this group of rare neurological disorders, especially when it presents with psychiatric symptoms. In this case, importance of neurological and radiological evaluation and need for high diagnostic suspicion in treatment-resistant psychiatric disorders is highlighted.

摘要

脑白质营养不良是一组脑脱髓鞘神经退行性疾病，表现多样，病因众多。预后大多不佳。在这组罕见的神经系统疾病中，误诊和错误治疗很常见，尤其是当出现精神症状时。在本病例中，强调了神经学和放射学评估的重要性以及对难治性精神障碍进行高度诊断怀疑的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce23/5385754/cbcfdaade9da/IJPsyM-39-202-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce23/5385754/cbcfdaade9da/IJPsyM-39-202-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce23/5385754/cbcfdaade9da/IJPsyM-39-202-g001.jpg

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