Das Aparna, Elwadhi Deeksha, Gupta Manushree
Department of Psychiatry, Maulana Azad Medical College, GB Pant Institute of Postgraduate Medical Education and Research, New Delhi, India.
Indian J Psychol Med. 2017 Mar-Apr;39(2):205-208. doi: 10.4103/0253-7176.203112.
Traumatic brain injury (TBI) can lead to changes in eating behavior patterns. This report describes the case of a patient with alcohol dependence presenting with behavioral changes and eating disorder following frontal lobe trauma. A 42-year-old male, premorbidly well-adjusted presented with alcohol use in dependent pattern for years. He sustained a subdural hematoma in the frontal lobe following a road traffic accident 10 years back. Post-TBI, the patient, started having low frustration tolerance, aggressive outbursts, disinhibition, difficulty in persisting with tasks, apathy, amotivation, and craving for food with inability to control intake on the sight of food. On testing, a deficit in frontal lobe functions was seen. Magnetic resonance imaging scan showed large areas of gliosis and encephalomalacia involving both frontal lobes with parenchymal loss. Eating disorders have been reported after TBI. This case report underscores a major role of frontal-subcortical circuits in regulation of eating habits.
创伤性脑损伤(TBI)可导致饮食行为模式的改变。本报告描述了一例酒精依赖患者在额叶创伤后出现行为改变和饮食障碍的病例。一名42岁男性,病前适应良好,多年来呈酒精依赖模式饮酒。10年前他在一次道路交通事故后额叶出现硬膜下血肿。创伤性脑损伤后,患者开始出现低挫折容忍度、攻击性爆发、行为脱抑制、难以坚持完成任务、冷漠、缺乏动机,以及看到食物就无法控制摄入量的食物渴望。经测试,发现额叶功能存在缺陷。磁共振成像扫描显示双侧额叶有大面积的胶质增生和脑软化,伴有实质损失。创伤性脑损伤后曾有饮食障碍的报道。本病例报告强调了额叶-皮质下回路在饮食习惯调节中的重要作用。