Drever L, Salomons G
Saskatoon Cancer Centre, Saskatoon SK.
CCSEO, Kingston ON.
Med Phys. 2012 Jul;39(7Part3):4630. doi: 10.1118/1.4740137.
Statistical process control (SPC) methods were used to analyze 239 measurement based individual IMRT QA events. The selected IMRT QA events were all head and neck (H&N) cases with 70Gy in 35 fractions, and all prostate cases with 76Gy in 38 fractions planned between March 2009 and 2012. The results were used to determine if the tolerance limits currently being used for IMRT QA were able to indicate if the process was under control. The SPC calculations were repeated for IMRT QA of the same type of cases that were planned after the treatment planning system was upgraded from Eclipse version 8.1.18 to version 10.0.39. The initial tolerance limits were found to be acceptable for two of the three metrics tested prior to the upgrade. After the upgrade to the treatment planning system the SPC analysis found that the a priori limits were no longer capable of indicating control for 2 of the 3 metrics analyzed. The changes in the IMRT QA results were clearly identified using SPC, indicating that it is a useful tool for finding changes in the IMRT QA process. Routine application of SPC to IMRT QA results would help to distinguish unintentional trends and changes from the random variation in the IMRT QA results for individual plans.
采用统计过程控制(SPC)方法分析了239个基于测量的个体化调强放疗(IMRT)质量保证事件。所选的IMRT质量保证事件均为2009年3月至2012年期间计划的头颈部(H&N)病例,剂量为70Gy,分35次照射,以及所有前列腺病例,剂量为76Gy,分38次照射。结果用于确定当前用于IMRT质量保证的公差限度是否能够表明过程是否处于控制之中。对治疗计划系统从Eclipse 8.1.18版升级到10.0.39版后计划的相同类型病例的IMRT质量保证重复进行SPC计算。发现升级前测试的三个指标中的两个,初始公差限度是可接受的。治疗计划系统升级后,SPC分析发现,先验限度不再能够表明所分析的三个指标中的两个处于控制之中。使用SPC可以清楚地识别IMRT质量保证结果的变化,表明它是发现IMRT质量保证过程中变化的有用工具。将SPC常规应用于IMRT质量保证结果将有助于区分个体计划的IMRT质量保证结果中的随机变化与无意的趋势和变化。