Hansson L, Choudry N B, Fuller R W, Pride N B
Department of Clinical Pharmacology, Royal Postgraduate Medical School, London.
Thorax. 1988 Nov;43(11):935-6. doi: 10.1136/thx.43.11.935.
In six normal subjects treatment with 4 mg nedocromil sodium failed to alter the cough and bronchoconstriction induced by inhaled capsaicin. Because nedocromil has previously been shown to inhibit reflex bronchoconstriction provoked by inhaled sulphur dioxide and inhaled bradykinin, the results suggest that inhaled capsaicin acts on different nerve fibres.
在6名正常受试者中,4毫克奈多罗米钠治疗未能改变吸入辣椒素所诱发的咳嗽和支气管收缩。由于奈多罗米此前已被证明可抑制吸入二氧化硫和吸入缓激肽所诱发的反射性支气管收缩,这些结果表明吸入辣椒素作用于不同的神经纤维。