Kim T, Yoon J, Kang S, Suh T
The Catholic University of Korea.
Med Phys. 2012 Jun;39(6Part8):3684. doi: 10.1118/1.4734973.
The purpose of this study was to analysis the residual motion artifact in 4D-CT scan using a simple one-dimension theoretical model.
In order to evaluate the target displacement at each phase image, We used phantom (Dynamic Thorax Phantom, CIRS, Norfolk, VA) which could control programmable regular 1D sine motion and belt type respiratory monitoring system. 2cm diameter spherical target was inserted in the phantom and then we set-up regular 1D sine motion and adjusted three level of amplitude (10, 20, 30 mm) with fixed period (4s). Four dimensional (4D) CT images were acquired by CT scanner (Sensation Open, Siemens Medical Systems, Forchheim, Germany) with a slice thickness of 1.5 mm and 0.1 pitch in helical mode. Respiratory monitoring system (AZ-733V, Anzai MEDICAL) was placed on the abdominal surface of phantom, and the respiratory signal was acquired. CorePLAN (RTP, SC&J) software was used to acquire static target diameter and each ten phase diameters.
The displacements (?S) peak at the 20∼30% or 70∼80% phases, and are minimized at the 50% phase. This is because the target velocity is minimum at 50% phase and maximum at 30 and 70% phases; hence, the large image blur. The measured diameters of target are compared to the simulation results and we observed similar trends of target diameter change.
In this study, we presented simple one-dimensional model to analyze the residual motion artifact in 4D-CT scan. The model was used to explain the effect of residual motion on each phase target displacement and also shown that residual motion artifact was affected that the target velocity at each phase. Lastly based on this model, we developed simulation program and acquired similar results of target displacement compared with measured data. This research was supported by Leading Foreign Re-search Institute Recruitment Program through the National Research Foundation of Korea (NFR) (Grant No. K20901000001-09E0100-00110,) and the program of Basic Atomic Energy Research Institute (BAERI) which is a part of the Nuclear R and D Programs (No.20110006324) funded by the Ministry of Education, Science and Technol-ogy(MEST).
本研究旨在使用一个简单的一维理论模型分析4D-CT扫描中的残余运动伪影。
为了评估每个相位图像上目标的位移,我们使用了可控制可编程规则一维正弦运动的体模(动态胸部体模,CIRS,弗吉尼亚州诺福克)和带式呼吸监测系统。将直径2cm的球形目标插入体模中,然后设置规则的一维正弦运动,并在固定周期(4s)下调整三个振幅水平(10、20、30mm)。通过CT扫描仪(Sensation Open,西门子医疗系统公司,德国福希海姆)以螺旋模式、1.5mm层厚和0.1螺距采集四维(4D)CT图像。将呼吸监测系统(AZ-733V,安斋医疗)放置在体模的腹部表面,采集呼吸信号。使用CorePLAN(RTP,SC&J)软件获取静态目标直径和每十个相位的直径。
位移(?S)峰值出现在20%至30%或70%至80%相位,在50%相位最小。这是因为目标速度在50%相位最小,在30%和70%相位最大;因此,图像模糊较大。将目标的测量直径与模拟结果进行比较,我们观察到目标直径变化的类似趋势。
在本研究中,我们提出了一个简单的一维模型来分析4D-CT扫描中的残余运动伪影。该模型用于解释残余运动对每个相位目标位移的影响,还表明残余运动伪影受每个相位目标速度的影响。最后,基于该模型,我们开发了模拟程序,并获得了与测量数据相比类似的目标位移结果。本研究得到了韩国国家研究基金会(NFR)的外国领先研究所招聘计划(批准号:K20901000001-09E0100-00110)以及由教育、科学和技术部(MEST)资助的核研发计划(编号:20110006324)的一部分基础原子能研究所(BAERI)计划的支持。