Trokart R, Demarche S, Schleich F, Paquot N, Louis R
Faculté de Médecine, Université de Liège, Belgique.
Pharmacie clinique et hospitalière, CHU de Liège, Site Sart Tilman, Liège, Belgique.
Rev Med Liege. 2017 May;72(5):241-245.
Asthma and obesity are both common diseases in western world. According to the data from our asthma clinic 20 % of our patients are obese and this rate increases up to 25 % in severe asthmatics included in the Belgian Severe Asthma national Registry. Alteration of thoracic mechanics contributes to greater symptom burden and poor asthma control in obese asthmatics. In particular the response to inhaled corticoids is attenuated. Weight loss results in a dramatic improvement in asthma control and should be a major goal in the asthma management of these patients.
哮喘和肥胖都是西方世界的常见疾病。根据我们哮喘诊所的数据，20%的患者肥胖，而在比利时严重哮喘国家登记处登记的重度哮喘患者中，这一比例高达25%。胸部力学改变导致肥胖哮喘患者的症状负担加重和哮喘控制不佳。特别是对吸入性皮质激素的反应减弱。体重减轻会使哮喘控制得到显著改善，应成为这些患者哮喘管理的主要目标。
