Piťha Jan
Vnitr Lek. 2017 Spring;63(4):272-276.
Patient drug adherence is a major problem especially in the prevention of cardiovascular disease of atherosclerotic origin. On one hand, antihypertensive drugs and hypolipidemic drugs/statins are among the most successful, ones the other hand, they are among the drugs which are most frequently skipped by the patients. Improvement could be realized by education of patients, more frequent follow-ups, as well as by the use of new technologies involving specific dispensers and other, even more sophisticated methods. Nevertheless, among the most successful strategies is the simplification of medication, particularly the use of drugs with a longer half-life and the use of combination of several drugs in a single tablet. Therefore, we have quite wide range of options to improve patient compliance. However, some disadvantages should be kept in mind associated with these techniques. The aim of this article is to discuss potential problems and solutions associated with patient adherence/compliance with respect to antihypertensive and hypolipidemic treatment with an emphasis on practical approach.Key words: drug adherence - dyslipidemia - hypertension - pharmacotherapy.
患者的药物依从性是一个主要问题,尤其是在预防动脉粥样硬化性心血管疾病方面。一方面,抗高血压药物和降血脂药物/他汀类药物是最成功的药物之一,另一方面,它们也是患者最常漏服的药物。可以通过对患者进行教育、更频繁的随访以及使用涉及特定配药器和其他更复杂方法的新技术来实现改善。然而,最成功的策略之一是简化用药,特别是使用半衰期更长的药物以及在单片制剂中使用几种药物的组合。因此,我们有相当广泛的选择来提高患者的依从性。然而,应该记住与这些技术相关的一些缺点。本文的目的是讨论与患者在抗高血压和降血脂治疗方面的依从性相关的潜在问题和解决方案,重点是实用方法。关键词:药物依从性 - 血脂异常 - 高血压 - 药物治疗