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与变应性肉芽肿性血管炎(Churg-Strauss综合征)相关的周围神经病:临床特征和组织学发现。

Peripheral neuropathy associated with allergic granulomatous angiitis (Churg-Strauss syndrome): clinical features and histological findings.

作者信息

Cavallaro T, Fenzi F, Lazzarino L G, Nicolai A, Rizzuto N, Valassi F

机构信息

Cattedra di Neuropatologia, Università di Verona.

出版信息

Ital J Neurol Sci. 1988 Dec;9(6):595-8. doi: 10.1007/BF02337014.

Abstract

We describe the case of a patient with a history of resistant asthma who presented with subacute neuropathy, hypereosiniphilia and central nervous system involvement; these findings were consistent with allergic granulomatous angiitis (Churg-Strauss syndrome). Although cutaneous biopsy prompted the diagnosis, the cases reported suggests that clinical, biological and histological data are all essential for the diagnosis. We emphasize that an early recognition of this syndrome may be important, since appropriate therapy may lead to recovery or influence favorably at least long term survival.

摘要

我们描述了一例有难治性哮喘病史的患者,该患者出现亚急性神经病变、嗜酸性粒细胞增多及中枢神经系统受累;这些表现符合变应性肉芽肿性血管炎(Churg-Strauss综合征)。尽管皮肤活检促成了诊断,但报告的病例表明临床、生物学及组织学数据对诊断均至关重要。我们强调,尽早识别该综合征可能很重要,因为恰当的治疗可能带来康复或至少对长期生存产生有利影响。

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