Yang Jing, Zhou Ying, Zhao Bin
Department of General Surgery, Seventh People's Hospital of Shanghai University of TCM, Shanghai, China.
Department of Gastroenterology, Seventh People's Hospital of Shanghai University of TCM, Shanghai, China.
J Clin Lab Anal. 2018 Jan;32(1). doi: 10.1002/jcla.22156. Epub 2017 May 19.
The patients diagnosed with pancreatic cancer have the possibilities of getting the cancer again even after resection. The tumor cells identified from blood can be related to different stages of tumor.
In this study, we used an immunoassay to detect circulating tumor cells in blood and bone marrow samples. About 120 patients' blood and bone marrow samples were used in this study along with controls. The presence of tumor cells was evaluated with different stages of cancer classified by UICC. The survival rate at each stages of tumor was also analyzed.
The tumor cells were isolated both in blood (29%) and bone marrow samples (25%). The prevalence of tumor cells increased with increase in stages of tumor in blood samples.
The survival of the patients considerably related to different stages of tumor but it cannot be taken a parameter alone for the patients' survival.
被诊断患有胰腺癌的患者即使在切除术后仍有再次患癌的可能性。从血液中鉴定出的肿瘤细胞可能与肿瘤的不同阶段有关。
在本研究中，我们使用免疫测定法检测血液和骨髓样本中的循环肿瘤细胞。本研究使用了约120名患者的血液和骨髓样本以及对照样本。根据国际抗癌联盟（UICC）分类的癌症不同阶段评估肿瘤细胞的存在情况。还分析了肿瘤各阶段的生存率。
在血液（29%）和骨髓样本（25%）中均分离出肿瘤细胞。血液样本中肿瘤细胞的患病率随肿瘤阶段的增加而增加。
患者的生存与肿瘤的不同阶段密切相关，但它不能单独作为患者生存的一个参数。
