Neri Iria, Lambertini Martina, Tengattini Vera, Rivalta Beatrice, Patrizi Annalisa
Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, Bologna, Italy.
Division of Pediatrics, University of Bologna, Bologna, Italy.
Pediatr Dermatol. 2017 May;34(3):e152-e153. doi: 10.1111/pde.13126.
An 8-month-old Caucasian infant with neurofibromatosis type 1 presented with a congenital plexiform neurofibroma and multiple café au lait spots. A pale area surrounded one of the café au lait spots located on the left gluteus in the area of dermal melanocytosis. This halolike phenomenon results from the disappearance of the Mongolian spot around the café au lait spots, revealing normal pigmented skin. This sign has been described rarely in the literature and the pathogenic mechanism is unclear.
一名患有1型神经纤维瘤病的8个月大高加索婴儿，患有先天性丛状神经纤维瘤和多个咖啡斑。位于左臀皮肤黑素细胞增多区域的一个咖啡斑周围有一片浅色区域。这种晕状现象是由于咖啡斑周围蒙古斑消失，露出正常色素沉着的皮肤所致。文献中很少描述这种体征，其发病机制尚不清楚。
