Steinberg B M
Department of Otolaryngology, Long Island Jewish Medical Center, New Hyde Park, New York 11042.
Ann N Y Acad Sci. 1988;549:118-28. doi: 10.1111/j.1749-6632.1988.tb23964.x.
Papillomaviruses are widespread, sexually transmitted agents with an increasing prevalence. They are associated with a significant risk of genital carcinoma in infected women. Because they can be transmitted to the fetus before or during birth, they are also a risk to the infant born to an infected woman. Laryngeal HPV infections, while presumably much less prevalent than genital tract infections, are associated with a high degree of morbidity and a significant degree of mortality when they cause laryngeal papillomas. Therefore, transmission of these viruses to the fetus is a major problem. Much more information regarding mode of transmission and possible cure for this infection is needed in order to reduce the risk of laryngeal papillomatosis in infants in the future.
乳头瘤病毒广泛存在,是通过性传播的病原体,其流行率不断上升。它们与感染女性患生殖器癌的重大风险相关。由于它们可在出生前或出生期间传播给胎儿,所以对感染女性所生婴儿也构成风险。喉乳头瘤病毒感染虽然推测远比生殖道感染少见,但当引起喉乳头状瘤时,会导致高度发病和显著死亡率。因此,这些病毒传播给胎儿是一个主要问题。为降低未来婴儿患喉乳头状瘤病的风险,需要更多关于传播方式和这种感染可能治疗方法的信息。