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F-FDG PET/CT有助于揭示极具迷惑性的病症:一例脊髓孤立受累的神经结节病病例。

F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis with isolated involvement of the spinal cord.

作者信息

Gholamrezanezhad A, Mehta L

机构信息

Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University, USA.

Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University, USA.

出版信息

Rev Esp Med Nucl Imagen Mol (Engl Ed). 2018 May-Jun;37(3):172-174. doi: 10.1016/j.remn.2017.02.013. Epub 2017 May 16.

Abstract

A 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord, as well as a mildly hypermetabolic bilateral hilar lymphadenopathy and a mildly hypermetabolic pulmonary nodule, suggestive of sarcoidosis versus metastasis. The diagnosis of sarcoidosis was supported by identifying non-caseating granuloma in the biopsy of the pulmonary nodule. The patient responded well to steroid-therapy, with the symptoms being resolved within 3 weeks.

摘要

一名36岁男性,既往无重大病史,出现下肢麻木、步态不稳以及大小便潴留4周。脊柱磁共振成像(MRI)显示颈胸段脊髓弥漫性水肿,伴有多个髓内实性强化病变,提示转移瘤。为确定原发性恶性肿瘤而进行的氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(F-FDG PET/CT)显示,颈胸段脊髓内有轻度代谢增高灶,以及双侧肺门轻度代谢增高的淋巴结病和一个轻度代谢增高的肺结节,提示结节病与转移瘤鉴别。肺结节活检发现非干酪样肉芽肿,支持结节病的诊断。患者对类固醇治疗反应良好,症状在3周内得到缓解。

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