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对比增强超声(CEUS)监测肝移植术后患者血管并发症的诊断准确性——与组织病理学结果比较的诊断性能

Diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in monitoring vascular complications in patients after liver transplantation - diagnostic performance compared with histopathological results.

作者信息

Rübenthaler J, Paprottka K J, Hameister E, Hoffmann K, Joiko N, Reiser M, Rjosk-Dendorfer D, Clevert D A

机构信息

Department of Clinical Radiology, Ludwig-Maximilians-University of Munich-Grosshadern Campus, Munich, Germany.

出版信息

Clin Hemorheol Microcirc. 2017;66(4):311-316. doi: 10.3233/CH-179105.

DOI:10.3233/CH-179105
PMID:28527202
Abstract

PURPOSE

To analyse the diagnostic performance of contrast-enhanced ultrasound (CEUS) in patients with vascular complications and transplant rejection compared to histopathological results.

MATERIALS AND METHODS

Our study consisted of 45 retrospectively analysed patients that underwent liver transplantations between January 1993 and December 2015 and developed post-transplant vascular complications with transplant rejection. CEUS examinations took place between September 2006 and December 2015. CEUS findings were correlated with histopathological results.

RESULTS

CEUS showed a sensitivity of 61.5%, a specificity of 100.0%, a positive predictive value (PPV) of 100.0% and a negative predictive value (NPV) of 86,5% in the detection of vascular complications with post-transplant rejection. 5 examinations were reported as normal whereas the histopathological result showed a transplant rejection (false-negative).

CONCLUSION

CEUS might be a useful additional non-invasive technique for the assessment of vascular complications with post-transplant rejection in patients after liver transplantation.

摘要

目的

与组织病理学结果相比,分析超声造影(CEUS)对血管并发症和移植排斥患者的诊断性能。

材料与方法

我们的研究包括45例回顾性分析的患者,这些患者在1993年1月至2015年12月期间接受了肝移植,并出现了移植后血管并发症伴移植排斥。CEUS检查在2006年9月至2015年12月期间进行。CEUS检查结果与组织病理学结果相关。

结果

在检测伴有移植排斥的血管并发症方面,CEUS的敏感性为61.5%,特异性为100.0%,阳性预测值(PPV)为100.0%,阴性预测值(NPV)为86.5%。有5次检查报告为正常,而组织病理学结果显示为移植排斥(假阴性)。

结论

CEUS可能是一种有用的辅助非侵入性技术,用于评估肝移植术后患者伴有移植排斥的血管并发症。

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