Bustos José, Sánchez Yasmin, Medina Jhon, Olivieri Rommy, Mojica Julián, Ortiz Johan
Departamento de Neurología, Hospital San Rafael, Tunja, Colombia Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia.
Biomedica. 2017 Apr 1;37(0):20-25. doi: 10.7705/biomedica.v37i2.2909.
Anti-N-methyl-D-aspartate receptor encephalitis is a neurological syndrome that is more common in young women and is often associated with ovarian teratoma. It is characterized by acute general unspecific symptoms that evolve to neurological deterioration, psychosis and seizures. In its more advanced stage it is associated with abnormal movements and dysautonomia.We report two cases in women of 23 and 12 years of age. Given its low incidence, we present the clinical exercise that led to their diagnoses and the treatment options employed.
抗N-甲基-D-天冬氨酸受体脑炎是一种神经综合征，在年轻女性中更为常见，且常与卵巢畸胎瘤相关。其特征为急性全身性非特异性症状，随后发展为神经功能恶化、精神病和癫痫发作。在疾病晚期，会出现异常运动和自主神经功能障碍。我们报告了两例分别为23岁和12岁女性的病例。鉴于其发病率较低，我们介绍了促成其诊断的临床过程以及所采用的治疗方案。
