被忽视热带病药物研发的未来：欧盟委员会如何持续发挥作用。

The Future of Drug Development for Neglected Tropical Diseases: How the European Commission Can Continue to Make a Difference.

作者信息

Pierce Raymond J, MacDougall Jane, Leurs Rob, Costi Maria Paola

机构信息

Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000 Lille, France.

Photeomix, IP Research Consulting SAS, Noisy le Grand, 93160, France.

出版信息

Trends Parasitol. 2017 Aug;33(8):581-583. doi: 10.1016/j.pt.2017.04.007. Epub 2017 May 18.

DOI:10.1016/j.pt.2017.04.007

PMID:28529130

Abstract

In this article, the four coordinators of neglected tropical disease (NTD) drug development projects funded under the European Commission (EC) Framework Programme 7 argue that the EC should reassess their funding strategy to cover the steps necessary to translate a lead compound into a drug candidate for testing in clinical trials, and suggest ways in which this might be achieved.

摘要

在本文中，由欧盟委员会（EC）第七框架计划资助的被忽视热带病（NTD）药物开发项目的四位协调员认为，欧盟委员会应重新评估其资助策略，以涵盖将先导化合物转化为可供临床试验测试的候选药物所需的各个步骤，并提出了实现这一目标的可能途径。