Abraham A S, Balkin J, Rosenmann D, Brooks B A, Eylath U, Zion M M
Department of Medicine, Shaare Zedek Medical Center, Jerusalem, Israel.
Cardiology. 1988;75(5):338-43. doi: 10.1159/000174396.
Fifteen patients (median age 73 years) with severe congestive heart failure were treated with Enalapril for a total of 12 weeks with a significant improvement in their right atrial pressures and in their functional state. Renal function, serum potassium, magnesium and calcium levels were unchanged. Lymphocyte sodium, potassium and calcium levels were generally lower than control values throughout the study but these differences were only statistically significant early in the study. Lymphocyte magnesium levels were unchanged. These findings are in contrast to those previously reported in the literature for such patients treated with conventional diuretics.
15名重度充血性心力衰竭患者（中位年龄73岁）接受依那普利治疗，为期12周，结果显示他们的右心房压力和功能状态有显著改善。肾功能、血清钾、镁和钙水平未发生变化。在整个研究过程中，淋巴细胞钠、钾和钙水平总体低于对照值，但这些差异仅在研究早期具有统计学意义。淋巴细胞镁水平未变。这些发现与先前文献中报道的使用传统利尿剂治疗此类患者的结果形成对比。
