Holroyd Suzanne, Sheldon-Keller Adrienne
Department of Psychiatric Medicine, University of Virginia School of Medicine.
Am J Geriatr Psychiatry. 1995;3(3):198-205. doi: 10.1097/00019442-199522330-00003. Epub 2012 Aug 15.
The authors screened 98 patients with probable Alzheimer's disease for visual hallucinations. Each patient with visual hallucinations was matched by cognitive score to two patients without visual hallucinations and compared on variables including visual acuity and visual agnosia. Eighteen (18.4%) of the patients were found to have visual hallucinations. Variables significantly associated with hallucinations included older age, female sex, decreased visual acuity, and presence of visual agnosia. Although having a history of visual disorder approached statistical significance, logistic regression analysis revealed that three variables: age, visual acuity in the "best eye," and visual agnosia, correctly classified 91% of patients as hallucinators vs. non-hallucinators. This work supports a growing body of research showing a relationship between visual hallucinations and the visual system across a variety of disorders.
作者对98名疑似阿尔茨海默病患者进行了视幻觉筛查。将每名有视幻觉的患者按认知得分与两名没有视幻觉的患者进行匹配，并在包括视力和视觉失认等变量上进行比较。发现18名（18.4%）患者有视幻觉。与幻觉显著相关的变量包括年龄较大、女性、视力下降和存在视觉失认。虽然有视觉障碍史接近统计学显著性，但逻辑回归分析显示，年龄、“最佳眼”的视力和视觉失认这三个变量能将91%的患者正确分类为幻觉者和非幻觉者。这项研究支持了越来越多的研究，这些研究表明视幻觉与各种疾病中的视觉系统之间存在关联。
