在越南北部恙虫病患者中鉴定出的恙虫病东方体基因型。
The genotypes of Orientia tsutsugamushi, identified in scrub typhus patients in northern Vietnam.
作者信息
Nguyen Hang L K, Pham Hang T T, Nguyen Tinh V, Hoang Phuong Vm, Le Mai T Q, Takemura Taichiro, Hasebe Futoshi, Hayasaka Daisuke, Yamada Akio, Hotta Kozue
机构信息
National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
105 Military Hospital, Hanoi, Vietnam.
出版信息
Trans R Soc Trop Med Hyg. 2017 Mar 1;111(3):137-139. doi: 10.1093/trstmh/trx022.
BACKGROUND
There are an estimated one million patients with scrub typhus in the Asia-Pacific region. There are few reports describing the incidence of scrub typhus in Vietnam.
METHODS
Blood samples collected from 63 patients clinically diagnosed as having scrub typhus from July 2015 to September 2016 were subjected to genotyping of Orientia tsutsugamushi.
RESULTS AND CONCLUSIONS
Of these patients, 42 (67%) tested positive for O. tsutsugamushi, and the most common genotype was identified to be Karp (55%). Other genotypes, TA763, Gilliam type in Japan variant, and Kato were also found in 17%, 17% and 12% of patients, respectively. To better understand the epidemiological landscape of scrub typhus in Vietnam, a countrywide study is needed.
ACCESSION NUMBERS
LC110330-LC110333, LC110336-LC110351 and LC214804-LC214825.
背景
据估计，亚太地区有100万恙虫病患者。关于越南恙虫病发病率的报道很少。
方法
对2015年7月至2016年9月期间临床诊断为恙虫病的63例患者采集的血样进行恙虫病东方体基因分型。
结果与结论
在这些患者中，42例（67%）恙虫病东方体检测呈阳性，最常见的基因型被确定为Karp型（55%）。其他基因型，TA763、日本变异株Gilliam型和Kato型分别在17%、17%和12%的患者中也有发现。为了更好地了解越南恙虫病的流行病学情况，需要进行全国性研究。
登录号
LC110330-LC110333、LC110336-LC110351和LC214804-LC214825。
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