From the Eye Center, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
From the Eye Center, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
J Cataract Refract Surg. 2017 Apr;43(4):486-491. doi: 10.1016/j.jcrs.2017.01.010.
To compare the outcomes between femtosecond laser-assisted cataract surgery (femtosecond group) and conventional phacoemulsification cataract surgery (conventional group) in patients with hard nuclear cataract.
Eye Center, Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, China.
Prospective consecutive nonrandomized comparative cohort study.
According to the Emery-Little classification, cataract patients with a grade 4 or 5 hard nuclei were assigned to 1 of the 2 groups. The endothelial cell density (ECD), central corneal thickness (CCT), and uncorrected and corrected (CDVA) distance visual acuities were evaluated preoperatively and 1 day, 1 week, 1 month, and 3 months postoperatively.
The study comprised 95 eyes (47 in the femtosecond group; 48 in the conventional group). The effective phacoemulsification time, absolute phaco time, and mean ultrasound power were lower in the femtosecond group (P < .001, P = .001, and P < .001, respectively). The ECD in the conventional group was lower and the changes in endothelial cell loss was different between the 2 groups throughout the follow-up (both P < .001). The CCT increased after surgery, and the thickness was greater in the conventional group at 1 day postoperatively (P < .05); it then returned to preoperative levels 1 month postoperatively in the femtosecond group and at 3 months in the conventional group. The CDVA was stable by 1 month postoperatively in the femtosecond group and by 3 months in the conventional group.
Compared with conventional phacoemulsification, femtosecond laser-assisted cataract surgery for hard nuclear cataracts conserved phacoemulsification power, provided a significant reduction in corneal endothelial damage, and led to faster visual rehabilitation.
比较飞秒激光辅助白内障手术（飞秒组）与传统超声乳化白内障手术（常规组）治疗硬核白内障的疗效。
浙江大学医学院附属第二医院眼科中心，中国杭州。
前瞻性连续非随机对照队列研究。
根据 Emery-Little 分类，将核硬度为 4 级或 5 级的白内障患者分为两组。评估术前、术后 1 天、1 周、1 个月和 3 个月时的内皮细胞密度（ECD）、中央角膜厚度（CCT）和未矫正及矫正距离视力（CDVA）。
本研究共纳入 95 只眼（飞秒组 47 只眼，常规组 48 只眼）。飞秒组的有效超声乳化时间、绝对超声乳化时间和平均超声能量均低于常规组（P<0.001、P=0.001 和 P<0.001）。常规组的 ECD 较低，两组之间整个随访期间的内皮细胞丢失变化不同（均 P<0.001）。术后 CCT 增加，常规组术后 1 天更厚（P<0.05）；飞秒组在术后 1 个月恢复术前水平，常规组在术后 3 个月恢复术前水平。飞秒组术后 1 个月 CDVA 稳定，常规组术后 3 个月稳定。
与传统超声乳化相比，飞秒激光辅助白内障手术治疗硬核白内障可节省超声乳化能量，显著减少角膜内皮损伤，并更快地恢复视力。
