From the Singapore National Eye Centre, Singapore.
From the Singapore National Eye Centre, Singapore.
J Cataract Refract Surg. 2017 Apr;43(4):564-569. doi: 10.1016/j.jcrs.2017.03.005.
Cataract surgery is a common procedure, and cystoid macular edema (CME) is a sight-threatening complication. Prostaglandin analogues are the first-line therapy for glaucoma, but their effect on the risk for CME after phacoemulsification is unknown. A systematic search of Medline and PubMed was performed to determine the effect of the use of prostaglandin analogues (PGA) on the development of CME after cataract surgery. A total of 412 articles were identified. Thirteen articles met inclusion criteria and were analyzed using Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) criteria. Prostaglandin analogue use was not associated with the development of clinically significant CME after cataract surgery regardless of the timepoint. There is no evidence for stopping PGA use prior to or during the course of cataract surgery to reduce CME, but caution should be exercised in complex eyes, which appear more susceptible to PGA-mediated CME.
白内障手术是一种常见的手术，而黄斑囊样水肿（CME）是一种威胁视力的并发症。前列腺素类似物是治疗青光眼的一线药物，但它们对白内障超声乳化术后发生 CME 的风险的影响尚不清楚。系统地检索了 Medline 和 PubMed，以确定使用前列腺素类似物（PGA）对白内障手术后 CME 发展的影响。共确定了 412 篇文章。符合纳入标准的有 13 篇文章，并使用观察性研究的报告质量评估工具（STROBE）标准进行了分析。无论在哪个时间点，使用前列腺素类似物与白内障手术后发生临床显著的 CME 无关。没有证据表明在白内障手术前或手术期间停止使用 PGA 可以减少 CME，但在复杂的眼睛中应谨慎使用，这些眼睛似乎更容易受到 PGA 介导的 CME 的影响。
