Paschali Anna N, Gnanasegaran Gopinath, Cook Gary J
Theagenion Cancer Hospital, Thessaloniki, Greece.
Royal Free London NHS Foundation Trust, London, UK.
Indian J Nucl Med. 2017 Apr-Jun;32(2):122-124. doi: 10.4103/0972-3919.202242.
Bleomycin-induced interstitial lung disease is not a rare complication of treatment and may prove to be fatal if not suspected early in its course. As FDG PET-CT has become an essential clinical tool for interim and end-of-treatment response assessment in oncology, it is important that radiologists/nuclear medicine specialists be aware of the features of this potentially treatable condition so that treatment can be instigated during an early reversible phase before pulmonary damage has occurred. Herein, we report two cases of bleomycin toxicity featuring different patterns on the treatment-response assessment FDG PET-CT scan.
博来霉素诱导的间质性肺病并非罕见的治疗并发症，若在病程早期未被怀疑，可能会致命。由于氟代脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（FDG PET-CT）已成为肿瘤学中评估治疗中期和末期反应的重要临床工具，放射科医生/核医学专家了解这种潜在可治疗疾病的特征非常重要，以便在肺部损伤发生前的早期可逆阶段就开始治疗。在此，我们报告两例博来霉素毒性病例，其在治疗反应评估FDG PET-CT扫描上呈现不同模式。
