Shamim Shamim Ahmed, Tripathy Sarthak, Mukherjee Anirban, Bal Chandrasekhar, Tripathi Madhavi
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Department of Nuclear Medicine, Eastern Diagnostics, Kolkata, India.
Indian J Nucl Med. 2017 Apr-Jun;32(2):162-163. doi: 10.4103/0972-3919.202253.
Central nervous system involvement is a rare manifestation of Langerhans cell histiocytosis (LCH), with bone and skin lesions being more frequent. MR remains the investigation of choice for localizing brain lesions. However, due to poor sensitivity of MRI in detecting osseous and pulmonary lesions, it is not used routinely in staging purposes until and unless indicated. We hereby discuss a case of 6-year-old boy of LCH who was referred for 18-F-FDG PET/CT for staging and knowing the extent of the disease, but a lesion in hypothalamus was picked up incidentally on FDG PET-CT study that was confirmed by MRI.
