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鼻脑型接合菌病:一名无危险因素的儿科心脏病患者的罕见显著表现。

Rhinocerebral zygomycosis: an unusual dramatic presentation in a paediatric cardiac patient without risk factors.

作者信息

Isgrò Giuseppe, Carlucci Concetta, Giamberti Alessandro, Frigiola Alessandro, Ranucci Marco

机构信息

IRCCS Policlinico San Donato, via Morandi, 30, 20097 San Donato Milanese, Italy.

出版信息

Eur Heart J Suppl. 2016 Apr 28;18(Suppl E):E19-E21. doi: 10.1093/eurheartj/suw029. Epub 2016 Apr 29.

Abstract

Mucormycosis is an angioinvasive infection caused by ubiquitous filamentous fungi of the order Mucorales. We describe a case of rhinocerebral mucormycosis presented in a paediatric patient after cardiac surgery correction of a complete atrioventricular canal defect. The rhinocerebral form of mucormycosis in our patient presented as an important epistaxis that needed immediate intubation due to blood inhalation. Furthermore, due to the worsening of pulmonary function, the patient also needed mechanical support with veno-arterial extracorporeal membrane oxygenation. The patient died as a consequence of a disseminated form of fungal infection. We describe our experience of this rare opportunistic infection and we think that early recognition of the disease could help in proper management.

摘要

毛霉病是由毛霉目无处不在的丝状真菌引起的一种血管侵袭性感染。我们描述了一例在小儿患者行完全性房室通道缺损心脏手术矫正后出现的鼻脑型毛霉病病例。我们患者的鼻脑型毛霉病表现为严重鼻出血,因血液吸入需要立即插管。此外,由于肺功能恶化,患者还需要静脉 - 动脉体外膜肺氧合进行机械支持。患者因播散性真菌感染而死亡。我们描述了我们对这种罕见机会性感染的经验,我们认为早期识别该疾病有助于进行适当的管理。

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