Pluchinotta Francesca Romana, Bussadori Claudio, Butera Gianfranco, Piazza Luciane, Chessa Massimo, Saracino Antonio, Fernandez Sarabia Javier, Giugno Luca, Arcidiacono Carmelo, Micheletti Angelo, Negura Diana Gabriela, Fesslova Vlasta, Carminati Mario
Department of Pediatric Cardiology and Adult Congenital Heart Disease - IRCCS Policlinico San Donato, San Donato Milanese (MI), Italy.
Eur Heart J Suppl. 2016 Apr 28;18(Suppl E):E22-E26. doi: 10.1093/eurheartj/suw019. Epub 2016 Apr 29.
The right timing to replace the pulmonary valve in a patient with dysfunction of the right ventricular outflow tract is unknown. Both percutaneous pulmonary valve and surgical prosthesis are suitable options. In every patient, the right ventricle (RV) remodels and recovers differently after pulmonary replacement. Therefore, it is difficult to identify the best treatment option and to predict the long-term results. In the last few years, we focused our research on optimizing the characterization of these patients through advanced cardiovascular imaging in order to find possible variables, parameters, and reproducible measurements that can help us in the decision-making process. The aim of the present article is to present our ongoing research lines that focus on the characterization and optimal treatment approach to the dysfunction of the RVOT.
对于右心室流出道功能障碍患者而言,肺动脉瓣置换的最佳时机尚不清楚。经皮肺动脉瓣和外科人工瓣膜都是合适的选择。每位患者在肺动脉置换术后,右心室(RV)的重塑和恢复情况各不相同。因此,很难确定最佳治疗方案并预测长期效果。在过去几年中,我们将研究重点放在通过先进的心血管成像技术优化这些患者的特征描述上,以便找到可能有助于我们进行决策的变量、参数和可重复测量方法。本文的目的是介绍我们正在进行的研究方向,这些研究方向聚焦于右心室流出道功能障碍的特征描述和最佳治疗方法。