Fares Salma, Lamchahab Mouna, Aniba Myriem, Lembarki Ghizlane, Mousalli Nadia, Regragui Meriem, Karkouri Mehdi, Quessar Asmaa
Service d'Hématologie et d'Oncologie Pédiatrique, Hôpital 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc.
Service de Radiologie de l'Hôpital 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc.
Pan Afr Med J. 2017 Mar 1;26:112. doi: 10.11604/pamj.2017.26.112.10304. eCollection 2017.
To better understand this cancer, we here report the case of a 43-year old patient diagnosed with localized and isolated primary colonic NK/T-cell lymphoma without associated enteropathy, treated wih 3 cycles of AspaMetDex with a poor response who died during treatment with a clinical picture of acute abdomen. Primary intestinal NK/T-cell lymphoma most commonly affects the young subject with poor prognosis. It is difficult to distinguish between intestinal NK/T-cell lymphoma and inflammatory or infectious intestinal disorders because of its non-specific clinical and endoscopic features. The histopathological and immunohistochemical data as well as the study of DNA allow to adjust the diagnosis and to classify this lymphoma according the European Enteropathy type T-cell lymphoma (ETL).
为了更好地了解这种癌症，我们在此报告一例43岁患者的病例，该患者被诊断为局限性孤立性原发性结肠NK/T细胞淋巴瘤，无相关肠病，接受了3个周期的天冬酰胺酶-甲氨蝶呤-地塞米松（AspaMetDex）治疗，但反应不佳，在治疗期间因急腹症临床表现死亡。原发性肠道NK/T细胞淋巴瘤最常影响年轻患者，预后较差。由于其非特异性的临床和内镜特征，肠道NK/T细胞淋巴瘤与炎症性或感染性肠道疾病难以区分。组织病理学和免疫组化数据以及DNA研究有助于调整诊断，并根据欧洲肠病型T细胞淋巴瘤（ETL）对该淋巴瘤进行分类。
