Antonijevic Aleksandar, Rancic Natasa, Ilic Mirko, Tiodorovic Branislav, Stojanovic Miodrag, Stevanovic Jasmina
Center for Public Health Kosovska Mitrovica, Serbia.
J BUON. 2017 Mar-Apr;22(2):508-512.
Ovarian cancer (OC) is the most fatal cancer in females. The objective of this paper was to determine the incidence and mortality trends of OC in central Serbia from 1999 to 2003.
Data about all new cases and deaths of OC were obtained from the Serbian Cancer Registry. Data were analyzed for the central of Serbia which encompasses the territory of Serbia without its northern and southern regions. Data of the female population were obtained from the population censuses in the years 1991, 2002 and 2011. World population was used as a standard. Trend and annual percentage change (APC) of the incidence and mortality rate with corresponding 95% confidence intervals (CI) were calculated by performing jointpoint regression.
Jointpoint analysis showed increased incidence trend of annual standardized rate (ASR) for OC from 1999 to 2013 with APC 0.3% (95%CI: 0.3, 0.8). Significantly increased trend in OC mortality was recorded continuously from 1999 to 2007 with APC 2.25% (95% CI: 0.9, 3.6). Decreased mortality trend was observed in the period 2010- 2013 with APC -7.34% (95%CI:-15.8, 2.0). The majority of the new cases of OC were aged 40-74 (78.7%). OC was the sixth most common cancer of all cancers in females and the sixth most common cause of cancer death in females.
During 1999-2013 there was an increasing trend of incidence of OC. In 1999-2007 there was a significant increasing mortality trend and non-significant decrease of the trend from 2010 to 2013 in central Serbia. The incidence and mortality rates of OC in central Serbia were higher than the corresponding rates in neighboring countries.
卵巢癌（OC）是女性中最致命的癌症。本文的目的是确定1999年至2003年塞尔维亚中部地区卵巢癌的发病率和死亡率趋势。
所有卵巢癌新发病例和死亡数据均来自塞尔维亚癌症登记处。对塞尔维亚中部地区的数据进行分析，该地区包括塞尔维亚除北部和南部地区之外的领土。女性人口数据来自1991年、2002年和2011年的人口普查。以世界人口作为标准。通过进行连接点回归计算发病率和死亡率的趋势及年度百分比变化（APC）以及相应的95%置信区间（CI）。
连接点分析显示，1999年至2013年卵巢癌年度标准化率（ASR）呈上升趋势，APC为0.3%（95%CI：0.3，0.8）。1999年至2007年卵巢癌死亡率持续显著上升，APC为2.25%（95%CI：0.9，3.6）。2010年至2013年期间观察到死亡率呈下降趋势，APC为-7.34%（95%CI：-15.8，2.0）。大多数卵巢癌新发病例年龄在40 - 74岁（78.7%）。卵巢癌是女性所有癌症中第六大常见癌症，也是女性癌症死亡的第六大常见原因。
1999年至2013年期间，卵巢癌发病率呈上升趋势。1999年至2007年死亡率显著上升，2010年至2013年趋势非显著下降，在塞尔维亚中部地区。塞尔维亚中部地区卵巢癌的发病率和死亡率高于邻国相应水平。
