小檗碱作为天然杀菌剂的评估：生物降解及抗菌机制
Evaluation of berberine as a natural fungicide: biodegradation and antimicrobial mechanism.
作者信息
Li Ying, Yin Yi-Ming, Wang Xin-Yue, Wu Hao, Ge Xi-Zhen
机构信息
a Beijing Key Laboratory of Biomass Waste Resource Utilization , Biochemical Engineering College, Beijing Union University , Beijing 100023 , China.
出版信息
J Asian Nat Prod Res. 2018 Feb;20(2):148-162. doi: 10.1080/10286020.2017.1329300. Epub 2017 May 23.
Berberine (BBR) is a traditional Chinese medicine which recently was applied as a biological pesticide. Here, we studied the antimicrobial mode of BBR and its impact on soil bacterial diversity. BBR was more effective against fungi than bacteria due to the specific interaction between BBR and glucan. Also, BBR was degraded rapidly in soil, leading to the limited effect on soil bacterial diversity. Collectively, BBR is an environment-friendly pesticide and it is promising in dealing with fungal plant diseases.
黄连素（BBR）是一种传统中药，最近被用作生物农药。在此，我们研究了黄连素的抗菌模式及其对土壤细菌多样性的影响。由于黄连素与葡聚糖之间的特定相互作用，黄连素对真菌的效果比对细菌的效果更好。此外，黄连素在土壤中迅速降解，导致其对土壤细菌多样性的影响有限。总的来说，黄连素是一种环境友好型农药，在处理植物真菌病害方面具有广阔前景。
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