Hosaka A
Department of Ophthalmology, Asahikawa Medical College, Japan.
Acta Ophthalmol Suppl (1985). 1988;185:95-9. doi: 10.1111/j.1755-3768.1988.tb02677.x.
Vitreous fluorophotometry was performed in 165 eyes of 93 cases with various degrees of myopia. The age range was 10-39 years. On background of the significant correlation between the refractive diopter value and the length of vitreous cavity, a simulation model for myopia has been established for assessing the permeability of the blood-retinal barrier. Significant negative correlations between the diopter and P-in and the diopter and D-p were found, indicating that by increasing degree of myopia, the functional disorder of the blood-retinal barrier and the liquefaction of the posterior vitreous gel progress. From the comparative study between eyes with slight myopia and eyes with emmetropia, a significant increase in the length of the vitreous cavity and P-in was found in the former, whereas no significant difference was observed in D-p. Therefore, it is suggested that the functional disorder of the blood-retinal barrier in myopia produces the liquefaction of the posterior vitreous gel.
对93例不同程度近视患者的165只眼进行了玻璃体荧光光度测定。年龄范围为10至39岁。在屈光度数与玻璃体腔长度之间存在显著相关性的背景下，建立了一个近视模拟模型，用于评估血视网膜屏障的通透性。发现屈光度与P-in以及屈光度与D-p之间存在显著负相关，表明随着近视程度的增加，血视网膜屏障的功能障碍和玻璃体后凝胶的液化进展。通过对轻度近视眼和正视眼的比较研究，发现前者的玻璃体腔长度和P-in显著增加，而D-p未观察到显著差异。因此，提示近视时血视网膜屏障的功能障碍导致了玻璃体后凝胶的液化。
