1Department of Psychiatry,Trakya University Hospital,Edirne,Turkey.
2Psychosis Research Unit,Department of Clinical Medicine,Aarhus University,Risskov,Denmark.
Acta Neuropsychiatr. 2018 Jun;30(3):175-180. doi: 10.1017/neu.2017.15. Epub 2017 May 24.
Recently, a semi-structured interview dedicated to aid rating on the Psychotic Depression Assessment Scale (PDAS) was developed. Here, we aimed to validate PDAS ratings collected via this semi-structured interview.
A total of 50 patients with psychotic depression - 34 with unipolar psychotic depression and 16 with bipolar psychotic depression - were recruited for the study. The following aspects of validity were investigated: clinical validity, psychometric validity (scalability), and responsiveness.
The PDAS ratings were clinically valid (Spearman's coefficient of correlation between PDAS total scores and Clinical Global Impressions scale - severity of illness ratings=0.66, p<0.001), scalable (Loevinger's coefficient of heterogeneity at endpoint=0.45), and responsive (no participants met the criterion for remission on the PDAS (total score <8) at baseline - at endpoint 74% (95% CI: 60-85) of the participants met this criterion).
The semi-structured PDAS interview provides valid ratings of the severity of psychotic depression.
最近，开发了一种专门用于辅助精神病性抑郁症评估量表（PDAS）评分的半结构式访谈。在此，我们旨在验证通过这种半结构式访谈收集的 PDAS 评分。
共招募了 50 名患有精神病性抑郁症的患者 - 34 名单相精神病性抑郁症患者和 16 名双相精神病性抑郁症患者 - 用于研究。考察了以下方面的有效性：临床有效性、心理测量有效性（可扩展性）和反应性。
PDAS 评分具有临床有效性（PDAS 总分与临床总体印象量表 - 疾病严重程度评分之间的斯皮尔曼相关系数=0.66，p<0.001），可扩展性（终点时 Loevinger 的异质性系数=0.45），并且具有反应性（没有参与者在基线时符合 PDAS（总分<8）的缓解标准 - 在终点时，74%（95%CI：60-85）的参与者符合此标准）。
半结构式 PDAS 访谈可对精神病性抑郁症的严重程度进行有效评分。
