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脓毒性髋关节炎和慢性骨髓炎后股骨颈病理性骨折:勒米尔综合征的一种潜在并发症。

Pathological fracture of the femoral neck following septic coxitis and chronic osteomyelitis: a potential complication of Lemierre's syndrome.

作者信息

Vogt Dominik Maximilian, Tüshaus Ludger, Kaiser Martin, Russlies Martin

机构信息

Klinik für Orthopädie und Unfallchirurgie, Universitatsklinikum Schleswig Holstein - Campus Lübeck, Lübeck, Germany.

Klinik für Kinderchirurgie, Universitatsklinikum Schleswig Holstein - Campus Lübeck, Lübeck, Germany.

出版信息

BMJ Case Rep. 2017 May 22;2017:bcr-2016-218474. doi: 10.1136/bcr-2016-218474.

Abstract

We portray the case of a 16-year-old girl who was initially admitted to the paediatric emergency department with non-specific symptoms of a severe cold and was first treated symptomatically on an ambulatory basis. Within 6 days she developed the full clinical picture of Lemierre's syndrome with the extraordinary manifestation of involvement of her right hip. Despite an interdisciplinary coordinated treatment as well as surgical therapy, a full-blown sepsis evolved within a short time period and resulted in almost 2 months of intensive care. While the primary focus could be successfully controlled, a progressive avascular necrosis of the right proximal femur developed on the basis of a chronic osteomyelitis. This finally led to a pathological fracture of the femoral neck. After excluding the possibility of an enduring bacterial infection, the fracture was treated with a total hip replacement.

摘要

我们描述了一名16岁女孩的病例,她最初因重感冒的非特异性症状被收治入儿科急诊科,最初在门诊进行对症治疗。6天内,她出现了勒米尔综合征的完整临床表现,右髋受累表现异常。尽管进行了多学科协调治疗以及手术治疗,但短期内仍发展为严重脓毒症,导致近2个月的重症监护。虽然原发灶得以成功控制,但右股骨近端基于慢性骨髓炎发展为进行性无菌性坏死。这最终导致股骨颈病理性骨折。在排除持续性细菌感染的可能性后,骨折通过全髋关节置换术进行治疗。

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Lemierre's syndrome; a rare cause of septic arthritis.勒米尔综合征;脓毒性关节炎的罕见病因。
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本文引用的文献

2
[Treatment of septic arthritis of the hip in children and adolescents].[儿童及青少年髋关节化脓性关节炎的治疗]
Z Orthop Unfall. 2013 Dec;151(6):596-602. doi: 10.1055/s-0033-1350933. Epub 2013 Dec 17.
3
Lemierre syndrome: more than just a sore throat.勒米尔综合征:不仅仅是喉咙痛。
BMJ Case Rep. 2013 Nov 28;2013:bcr2013201868. doi: 10.1136/bcr-2013-201868.
6
[Arthroscopic therapy algorithm for septic coxitis].[化脓性髋关节炎的关节镜治疗算法]
Unfallchirurg. 2012 Nov;115(11):972-6. doi: 10.1007/s00113-012-2203-2.
9
Eponym: the Lemierre syndrome.译名:勒米厄尔综合征。
Eur J Pediatr. 2010 Apr;169(4):411-4. doi: 10.1007/s00431-009-1135-5. Epub 2010 Jan 28.
10
Lemierre syndrome: a pediatric case series and review of literature.勒米厄尔综合征:儿科病例系列及文献复习。
Am J Otolaryngol. 2010 Jan-Feb;31(1):38-45. doi: 10.1016/j.amjoto.2008.09.006. Epub 2009 Mar 26.

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