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肠外脓肿:一种罕见的并发症。

extraintestinal abscess: a rare complication.

作者信息

Kantamaneni Vamsi Krishna, Gurram Krishna C, Kulkarni Abhijit

机构信息

Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

Gastroenterology, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

出版信息

BMJ Case Rep. 2017 May 22;2017:bcr-2017-219957. doi: 10.1136/bcr-2017-219957.

DOI:10.1136/bcr-2017-219957
PMID:28536228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5753697/
Abstract

Extraintestinal is rare. A 74-year-old man with a history of ulcerative colitis presented after a fall. Trauma work-up showed liver cirrhosis. Two days later he developed abdominal pain, distension, diarrhoea and leucocytosis. Stool tested positive for CT abdomen showed pancolitis with toxic megacolon. Total abdominal colectomy and ileostomy with a rectal stump was performed. He was discharged, but was readmitted with sepsis. CT abdomen showed a 10.4×7.2 cm fluid collection in the pelvis. stool was negative. CT-guided abscess drainage grew Barium enema was negative for communication from the rectal stump to the abscess. The patient was treated with metronidazole for 2 weeks. In summary, extraintestinal can develop from recent antibiotics use, gastrointestinal surgery and microperforations from toxic megacolon. We recommend abscess drainage, concomitant treatment with metronidazole and or vancomycin, and reimaging of abscess location 2-4 weeks after cessation of antibiotics.

摘要

肠外并发症较为罕见。一名有溃疡性结肠炎病史的74岁男性在跌倒后就诊。创伤检查显示肝硬化。两天后,他出现腹痛、腹胀、腹泻和白细胞增多。粪便检测呈阳性,腹部CT显示全结肠炎伴中毒性巨结肠。进行了全腹结肠切除术及带直肠残端的回肠造口术。他出院了,但因脓毒症再次入院。腹部CT显示盆腔有一个10.4×7.2厘米的液性包块。粪便检测为阴性。CT引导下脓肿引流培养出……钡灌肠显示直肠残端与脓肿之间无相通。患者接受甲硝唑治疗2周。总之,肠外并发症可由近期使用抗生素、胃肠道手术以及中毒性巨结肠的微小穿孔引起。我们建议进行脓肿引流,同时使用甲硝唑和/或万古霉素治疗,并在停用抗生素2 - 4周后对脓肿位置进行再次成像。

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Mayo Clin Proc. 2014 Nov;89(11):1525-36. doi: 10.1016/j.mayocp.2014.07.012. Epub 2014 Sep 20.
2
Multistate point-prevalence survey of health care-associated infections.多州医疗机构相关性感染的时点患病率调查。
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Extraintestinal Clostridium difficile infections.肠道外艰难梭菌感染。
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Colonic microbiome is altered in alcoholism.肠道微生物组在酒精中毒中发生改变。
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Two case reports of Clostridium difficile bacteremia, one with the epidemic NAP-1 strain.两例艰难梭菌菌血症病例报告,其中一例为流行的NAP-1 株。
Infection. 2011 Aug;39(4):371-3. doi: 10.1007/s15010-011-0115-7. Epub 2011 Apr 21.
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Monomicrobial Clostridium difficile bacteraemias and relationship to gut infection.单一微生物艰难梭菌菌血症及其与肠道感染的关系。
J Hosp Infect. 2011 Feb;77(2):170-1. doi: 10.1016/j.jhin.2010.06.024. Epub 2010 Dec 3.
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Comparative metagenomic study of alterations to the intestinal microbiota and risk of nosocomial Clostridum difficile-associated disease.比较肠道微生物组改变与医院获得性艰难梭菌相关疾病风险的宏基因组学研究。
J Infect Dis. 2010 Dec 15;202(12):1877-84. doi: 10.1086/657319. Epub 2010 Nov 4.
8
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