Kanamori Min, Kurumiya Yasuhiro, Mizuno Keisuke, Sekoguchi Ei, Kobayashi Satoshi, Fukami Yasuyuki, Kiriyama Muneyasu, Aoyama Hiroki, Oiwa Takashi, Miyamura Kei, Jinno Takanori, Nakashima Yu, Mori Makiko
Dept. of Surgery, Toyota Kosei Hospital.
Gan To Kagaku Ryoho. 2017 May;44(5):417-420.
The patient was a 66-year-old woman with a history of right breast cancer 20 years prior. Her chief complaint was hematochezia, and she was diagnosed as having rectal cancer. She underwent laparoscopic high anterior resection. We made a diagnosis of moderately differentiated adenocarcinoma, type 2, 25×20 mm, pMP, pN0, Stage I, KRAS being wild-type. Multiple liver metastases were detected 6 months after the surgery. Tumor contacted with grison. The tumor was not completely resected as evidenced by the small liver remnant volume. Conversion therapy was administered, and the patient received 6 courses of FOLFIRI plus cetuximab therapy. Alopecia and grade 1 eruption were observed as adverse effects of the chemotherapy. The tumor size was reduced, and we resected the tumor by performing right lobectomy and partial hepatectomy. At 1 year 3 months after surgery, no recurrence was observed.
该患者为一名66岁女性，20年前有右乳腺癌病史。她的主要症状是便血，被诊断为直肠癌。她接受了腹腔镜高位前切除术。我们诊断为中度分化腺癌，2型，大小为25×20 mm，pMP，pN0，I期，KRAS基因野生型。术后6个月检测到多发肝转移。肿瘤与肝组织粘连。由于肝残留体积小，肿瘤未完全切除。给予转化治疗，患者接受了6个疗程的FOLFIRI联合西妥昔单抗治疗。观察到化疗的不良反应为脱发和1级皮疹。肿瘤大小缩小，我们通过右叶切除术和部分肝切除术切除了肿瘤。术后1年3个月未观察到复发。
