Reinehr Clarissa P H, Garbin Gabriela C, Bakos Renato M
*All authors are affiliated with the Department of Dermatology, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Dermatol Surg. 2017 Nov;43(11):1385-1391. doi: 10.1097/DSS.0000000000001210.
Actinic keratoses (AKs) are dysplastic proliferations of keratinocytes. Studies evaluating nonfacial dermatoscopic pattern of AKs are scarce.
This study aimed to evaluate the dermatoscopic patterns of AKs located in nonfacial sites and to compare their patterns with facial lesions.
Patients with concomitant facial and nonfacial AKs were recruited to participate and evaluated by clinical and dermatoscopic images of their AKs.
Sixty-eight patients were included in the study. A total of 258 nonfacial AKs and 68 facial AKs were analyzed. The most frequent nonfacial AK dermatoscopic structures were white opaque scales (97.3%) and erythema (57.4%). When analyzed in combination, white scales plus erythema were found in 55.4% of nonfacial AKs. Pigmented structures were observed in 22.5% nonfacial AKs. Homogeneous brown pigmentation was the most prevalent pigmented structure in nonfacial pigmented AK (pAK) (93.1%). There was a positive association between patients having concomitant pigmented facial and nonfacial AKs (p < .001).
The combinations of erythema and white opaque scales or yellow opaque scales and homogeneous pigmentation are suggestive, respectively of nonpigmented and pigmented nonfacial AKs. Pigmented AKs occur concomitantly in facial and nonfacial areas.
光化性角化病(AK)是角质形成细胞的发育异常增殖。评估AK非面部皮肤镜表现的研究较少。
本研究旨在评估非面部部位AK的皮肤镜表现,并将其与面部病变的表现进行比较。
招募患有面部和非面部AK的患者参与研究,并通过其AK的临床和皮肤镜图像进行评估。
68例患者纳入本研究。共分析了258个非面部AK和68个面部AK。非面部AK最常见的皮肤镜结构是白色不透明鳞屑(97.3%)和红斑(57.4%)。综合分析时,55.4%的非面部AK出现白色鳞屑加红斑。22.5%的非面部AK观察到色素沉着结构。均匀棕色色素沉着是非面部色素性AK(pAK)中最常见的色素沉着结构(93.1%)。面部和非面部同时出现色素性AK的患者之间存在正相关(p <.001)。
红斑与白色不透明鳞屑或黄色不透明鳞屑以及均匀色素沉着的组合分别提示非色素性和色素性非面部AK。色素性AK同时出现在面部和非面部区域。