Ertaş Kerem, Salihoğlu Özgül, Can Emrah, Hatipoğlu Sami, Hamilçikan Şahin
*Department of Pediatrics, Bakirkoy Dr. Sadi Konuk Training and Research, Hospital †Department of Pediatrics, Bağcilar Training and Research, Hospital, Istanbul, Turkey.
J Pediatr Hematol Oncol. 2017 Nov;39(8):e426-e429. doi: 10.1097/MPH.0000000000000854.
Fetal malnutrition is especially important for common chronic diseases in adult life. They could potentially be prevented by achieving optimal fetal nutrition.
The aim of this study was to investigate hematocrit levels of malnourished, term, appropriate for gestational age (AGA) neonates.
A total of 80 AGA neonates (between 10% and 90% percentiles interval according to birth week), born with spontaneous vaginal delivery between 37 and 42 weeks of gestation, detected by both last menstrual period and ultrasonography measurements, were included in the study. Neonates with fetal malnutrition constituted the study group and the control group consisted of well-nourished neonates. We analyzed central venous hematocrit levels obtained 4 hours after birth and maternal risk factors for both groups.
Although there were no differences in gestational age, head circumference, maternal factors (gravidity, parity, abortions and curettage counts, maternal tobacco use, preeclampsia, hypertension, diabetes mellitus, gestational diabetes mellitus, and history of urinary tract infections), first minute APGAR scores, and sex, Clinical Assessment of Nutritional Status score was lower (29.91±2.87 vs. 21.25±1.65) and hematocrit levels were higher (51.33±2.740 vs. 59.53±5.094) in the fetal malnutrition group (P<0.0001).
Central hematocrit levels in malnourished term AGA neonates were found significantly higher than well-nourished term AGA newborns.
胎儿营养不良对成年后的常见慢性病尤为重要。通过实现最佳胎儿营养，这些疾病有可能得到预防。
本研究旨在调查足月、适于胎龄（AGA）的营养不良新生儿的血细胞比容水平。
本研究纳入了80例AGA新生儿（根据出生周数处于第10至90百分位数区间），这些新生儿通过末次月经和超声测量确定为妊娠37至42周经阴道自然分娩。胎儿营养不良的新生儿构成研究组，对照组由营养良好的新生儿组成。我们分析了出生后4小时测得的中心静脉血细胞比容水平以及两组的母亲危险因素。
尽管两组在胎龄、头围母体因素（妊娠次数、产次、流产及刮宫次数、母亲吸烟、先兆子痫、高血压、糖尿病、妊娠期糖尿病及尿路感染史）、1分钟阿氏评分和性别方面无差异，但胎儿营养不良组的营养状况临床评估评分较低（29.91±2.87对21.25±1.65），血细胞比容水平较高（51.33±2.740对59.53±5.094）（P<0.0001）。
发现足月AGA营养不良新生儿的中心血细胞比容水平显著高于足月AGA营养良好的新生儿。
