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从颅外动脉延伸至颅内动脉的解剖:一例进展性缺血性卒中病例报告

Dissection extending from extra- to intracranial arteries: A case report of progressive ischemic stroke.

作者信息

Zhang Fu-Liang, Guo Zhen-Ni, Liu Yang, Luo Yun, Yang Yi

机构信息

Stroke Center Neuroscience Center, Department of Neurology Department of Radiology, the First Hospital of Jilin University, Chang Chun, China.

出版信息

Medicine (Baltimore). 2017 May;96(21):e6980. doi: 10.1097/MD.0000000000006980.

DOI:10.1097/MD.0000000000006980
PMID:28538402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5457882/
Abstract

RATIONALE

Cervicocephalic artery dissections, once considered a rare disease, have become increasingly recognized as a cause of stroke in young and middle-aged individuals. Early diagnosis is mandatory because anticoagulation or antithrombotic therapy can help prevent primary or secondary ischemic events. However, the diagnosis is still a crucial challenge for radiologists and neurologists.

PATIENT CONCERNS

We reported a rare case of 33-year-old patient with progressive ischemic stroke due to dissection from an intimal tear in the right proximal internal carotid artery to distal middle cerebral artery.

DIAGNOSES

3D fat-saturated T1 VISTA imaging, owing to its comprehensive neck and head coverage, high spatial resolution, enables the reader to have several sections with good contrast covering the dissected arterial segment, even in the rare dissection involving extra- and intra-cranial arteries referred in this article.

INTERVENTIONS

Clopidogrel 75mg daily was prescribed, also the patient was given rehabilitation training.

OUTCOMES

His symptoms improved gradually.

LESSONS

We describe that 3D fat-saturated T1 VISTA was helpful for the diagnosis and follow-up in our case of cervicocephalic artery dissection complicated with progressive ischemic stroke. However, for totally acute occlusion of the artery without typical features of dissection, the unequivocal distinction between intramural haematoma and intraluminal thrombus may still be difficult with 3D fat-saturated T1 VISTA alone. Future studies should investigate whether an optimal VISTA technique would be useful for making a definite diagnosis.

摘要

理论依据

颈脑动脉夹层,曾被认为是一种罕见疾病,如今越来越被视为中青年人群中风的一个病因。早期诊断至关重要,因为抗凝或抗血栓治疗有助于预防原发性或继发性缺血性事件。然而,对于放射科医生和神经科医生而言,诊断仍是一项严峻挑战。

患者情况

我们报告了一例罕见的33岁患者,因右颈内动脉近端至大脑中动脉远端的内膜撕裂夹层导致进行性缺血性中风。

诊断

3D脂肪饱和T1 VISTA成像,因其对颈部和头部的全面覆盖、高空间分辨率,即使在本文提及的累及颅外和颅内动脉的罕见夹层病例中,也能让阅片者获得多个对比度良好的层面,覆盖夹层动脉段。

干预措施

每日给予氯吡格雷75mg,同时对患者进行康复训练。

结果

他的症状逐渐改善。

经验教训

我们描述了3D脂肪饱和T1 VISTA对我们这例颈脑动脉夹层合并进行性缺血性中风病例的诊断和随访有帮助。然而,对于没有典型夹层特征的动脉完全急性闭塞,仅靠3D脂肪饱和T1 VISTA可能仍难以明确区分壁内血肿和腔内血栓。未来的研究应调查最佳的VISTA技术是否有助于做出明确诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfba/5457882/6181c15bc034/medi-96-e6980-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfba/5457882/ab6d644f57ab/medi-96-e6980-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfba/5457882/6181c15bc034/medi-96-e6980-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfba/5457882/ab6d644f57ab/medi-96-e6980-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfba/5457882/6181c15bc034/medi-96-e6980-g002.jpg

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MRI of intracranial vertebral artery dissection: evaluation of intramural haematoma using a black blood, variable-flip-angle 3D turbo spin-echo sequence.颅内椎动脉夹层的 MRI 检查:使用黑血、可变翻转角 3D 涡轮自旋回波序列评估壁内血肿。
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