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青少年特发性脊柱侧弯患者后路脊柱融合术后前2周内的术后伤口疼痛轨迹

Trajectory of Postoperative Wound Pain Within the First 2 Weeks Following Posterior Spinal Fusion Surgery in Adolescent Idiopathic Scoliosis Patients.

作者信息

Kwan Mun Keong, Chiu Chee Kidd, Chan Teik Seng, Chong Kok Ian, Mohamad Siti Mariam, Hasan Mohd Shahnaz, Chan Chris Yin Wei

机构信息

Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Department of Anaesthesiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Spine (Phila Pa 1976). 2017 Jun 1;42(11):838-843. doi: 10.1097/BRS.0000000000001902.

Abstract

STUDY DESIGN

A prospective cohort study.

OBJECTIVE

The aim of this study was to determine and evaluate the trajectory of surgical wound pain from day 1 to day 14 after posterior spinal fusion (PSF) surgery in patients with adolescent idiopathic scoliosis (AIS).

SUMMARY OF BACKGROUND DATA

Information regarding how the postoperative pain improves with time offers invaluable information not only to the patients and parents but also to assist the clinician in managing postoperative pain.

METHODS

AIS patients who were planned for elective PSF surgery from September 2015 to December 2015 were prospectively recruited into this study. All patients underwent a similar pain management regimen with patient-controlled anesthesia (PCA) morphine, acetaminophen, celecoxib, and oxycodone hydrochloride.

RESULTS

A total of 40 patients (36 F:4 M) were recruited. The visual analogue score (VAS) pain score was highest at 12 hours postoperation (6.0 ± 2.3). It reduced to 3.9 ± 2.2 (day 4), 1.9 ± 1.6 (day 7), and 0.7 ± 1.1 (day 14). The total PCA usage in all patients was 12.4 ± 9.9 mg (first 12 hours), 7.1 ± 8.0 mg (12 to 24 hours), 5.6 ± 6.9 (24-36 hours), and 2.1 ± 6.1 mg (36-48 hours). The celecoxib capsules usage was reducing from 215.0 ± 152.8 mg at 24 hours to 55.0 ± 90.4 mg on day 14. The acetaminophen usage was reducing from 2275 ± 1198 mg at 24 hours to 150 ± 483 mg at day 14. Oxycodone hydrochloride capsules consumption rose to the peak of 1.4 ± 2.8 mg on day 4 before gradually reducing to none by day 13.

CONCLUSION

With an adequate postoperation pain regimen, significant pain should subside to a tolerable level by postoperative day 4 and negligible by postoperative day 7. Patient usually can be discharged on postoperative day 4 when the usage of PCA morphine was not required.

LEVEL OF EVIDENCE

摘要

研究设计

前瞻性队列研究。

目的

本研究旨在确定并评估青少年特发性脊柱侧弯(AIS)患者后路脊柱融合术(PSF)后第1天至第14天手术伤口疼痛的轨迹。

背景数据总结

关于术后疼痛如何随时间改善的信息,不仅能为患者及其家长提供宝贵信息,还能帮助临床医生管理术后疼痛。

方法

前瞻性招募2015年9月至2015年12月计划接受择期PSF手术的AIS患者。所有患者均接受了类似的疼痛管理方案,包括患者自控镇痛(PCA)吗啡、对乙酰氨基酚、塞来昔布和盐酸羟考酮。

结果

共招募40例患者(36例女性:4例男性)。视觉模拟评分(VAS)疼痛评分在术后12小时最高(6.0±2.3)。在第4天降至3.9±2.2,第7天降至1.9±1.6,第14天降至0.7±1.1。所有患者的PCA总用量在术后前12小时为12.4±9.9mg,12至24小时为7.1±8.0mg,24至36小时为5.6±6.9mg,36至48小时为2.1±6.1mg。塞来昔布胶囊用量从术后24小时的215.0±152.8mg降至第14天的55.0±90.4mg。对乙酰氨基酚用量从术后24小时的2275±1198mg降至第14天的150±483mg。盐酸羟考酮胶囊用量在第4天升至峰值1.4±2.8mg,然后在第13天逐渐降至零。

结论

采用适当的术后疼痛管理方案,术后第4天显著疼痛应减轻至可耐受水平,术后第7天可忽略不计。当不需要使用PCA吗啡时,患者通常可在术后第4天出院。

证据级别

2级。

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