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大脑视觉区域对阅读流畅性的影响及定位:以具有阅读障碍特征的儿童为例。

The Location and Effects of Visual Hemisphere-Specific Stimulation on Reading Fluency in Children With the Characteristics of Dyslexia.

机构信息

1 University of Houston, TX, USA.

出版信息

J Learn Disabil. 2018 Jul/Aug;51(4):399-415. doi: 10.1177/0022219417711223. Epub 2017 May 24.

DOI:10.1177/0022219417711223
PMID:28539071
Abstract

Fluency is used as an indicator of reading proficiency. Many students with reading disabilities are unable to benefit from typical interventions. This study is designed to replicate Lorusso, Facoetti, Paganoni, Pezzani, and Molteni's (2006) work using FlashWord, a computer program that tachistoscopically presents words in the right or left visual hemi-field in English and locates through fMRI imaging the processing areas involved in fluency development. Our participants were 15 students who were ages 8 to 19 years and had reading disabilities randomly assigned to Intervention ( n = 9) and Delayed Intervention ( n = 6) groups. Functional imaging studies focused on analyzing activations in the left hemisphere (LH) superior temporal gyrus, the inferior frontal gyrus, and the LH inferior occipito-temporal/fusiform area (visual-word form area [VWFA]). Analysis of intervention data showed that 6 of the 9 Intervention group participants (67%) achieved levels of automatic processing and increased their reading rate by an average of 20 words per minute after participating in the FlashWord intervention. Analyses of fMRI group activation maps and mean activation levels in regions of interest document processing changes in VWFA activations that could be related to the increase in reading speed and confirm these locations as essential to developing fluency.

摘要

流畅度常被用作阅读水平的指标。许多阅读障碍学生无法从典型干预中受益。本研究旨在使用 FlashWord 复制 Lorusso、Facoetti、Paganoni、Pezzani 和 Molteni(2006 年)的工作,该程序以速示器的方式呈现英语单词,在左右视觉半视野中呈现单词,并通过 fMRI 成像定位参与流畅度发展的处理区域。我们的参与者是 15 名年龄在 8 到 19 岁之间、有阅读障碍的学生,他们被随机分配到干预组(n=9)和延迟干预组(n=6)。功能成像研究重点分析左半球(LH)颞上回、下额回和 LH 下枕颞/梭状回区(视词汇形区[VWFA])的激活。干预数据的分析表明,干预组的 9 名参与者中有 6 名(67%)达到了自动处理水平,并且在参加 FlashWord 干预后,他们的阅读速度平均提高了 20 个单词/分钟。对 fMRI 组激活图和感兴趣区域的平均激活水平的分析记录了 VWFA 激活的变化,这些变化可能与阅读速度的提高有关,并证实这些位置对发展流畅度至关重要。

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