视神经脊髓炎最新进展：自然史与管理
Update on neuromyelitis optica: natural history and management.
作者信息
Jindahra Panitha, Plant T
机构信息
The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
St Thomas' Hospital, Westminster Bridge Road, London, UK.
出版信息
Eye Brain. 2012 Mar 26;4:27-41. doi: 10.2147/EB.S8392. eCollection 2012.
Abstract
Neuromyelitis optica or Devic disease is an inflammatory disorder of the central nervous system. It is caused by antibodies that attack aquaporin 4 water channels in the cell membrane of astrocytic foot processes at the blood brain barrier. It can involve the optic nerve, the spinal cord and beyond. Here we review its pathophysiology, clinical features, and therapy.
摘要
视神经脊髓炎或德维克病是一种中枢神经系统的炎性疾病。它由攻击血脑屏障处星形胶质细胞足突细胞膜上的水通道蛋白4水通道的抗体引起。它可累及视神经、脊髓及其他部位。在此我们综述其病理生理学、临床特征及治疗方法。
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