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影像学在心力衰竭患者肾功能不全评估中的作用。

Role of imaging in the evaluation of renal dysfunction in heart failure patients.

作者信息

Grande Dario, Terlizzese Paola, Iacoviello Massimo

机构信息

Dario Grande, Paola Terlizzese, School of Cardiology, University of Bari, 70124 Bari, Italy.

出版信息

World J Nephrol. 2017 May 6;6(3):123-131. doi: 10.5527/wjn.v6.i3.123.

Abstract

Heart failure and kidney disease share common pathophysiological pathways which can lead to mutual dysfunction, known as cardiorenal syndrome. In heart failure patients, renal impairment is related to hemodynamic and non-hemodynamic factors. Both decreased renal blood flow and renal venous congestion due to heart failure could lead to impaired renal function. Kidney disease and worsening renal function are independently associated with poor prognosis in heart failure patients, both in acute and chronic clinical settings. The aim of this review is to assess the role of renal imaging modalities in the evaluation and management of heart failure patients. Renal imaging techniques could complete laboratory data, as estimated glomerular filtration rate, exploring different pathophysiological factors involved in kidney disease and adding valuable information about renal structure and function. In particular, Doppler examination of arterial and venous hemodynamics is a feasible and non invasive technique, which has proven to be a reliable method for prognostic stratification in patients with cardiorenal syndrome. The renal resistance index, a measure related to renal hemodynamics, can be calculated from the Doppler evaluation of arterial flow. Moreover, the analysis of Doppler venous flow patterns can integrate information from the arterial study and evaluate renal congestion. Other imaging modalities are promising, but still confined to research purposes.

摘要

心力衰竭和肾脏疾病具有共同的病理生理途径,可导致相互功能障碍,即所谓的心肾综合征。在心力衰竭患者中,肾功能损害与血流动力学和非血流动力学因素有关。心力衰竭导致的肾血流量减少和肾静脉淤血均可导致肾功能受损。在急性和慢性临床环境中,肾脏疾病和肾功能恶化均与心力衰竭患者的不良预后独立相关。本综述的目的是评估肾脏成像模式在心力衰竭患者评估和管理中的作用。肾脏成像技术可以完善实验室数据,如估计肾小球滤过率,探索肾脏疾病中涉及的不同病理生理因素,并提供有关肾脏结构和功能的有价值信息。特别是,动脉和静脉血流动力学的多普勒检查是一种可行的非侵入性技术,已被证明是心肾综合征患者预后分层的可靠方法。肾阻力指数是一种与肾血流动力学相关的指标,可通过动脉血流的多普勒评估来计算。此外,对多普勒静脉血流模式的分析可以整合动脉研究的信息并评估肾淤血。其他成像模式很有前景,但仍局限于研究目的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99d7/5424434/046c44e5437f/WJN-6-123-g001.jpg

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