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迎来阴茎移植时代。

Ushering in the era of penile transplantation.

作者信息

Rasper Alison M, Terlecki Ryan P

机构信息

Department of Urology, Wake Forest Baptist Health, Winston-Salem, NC, USA.

出版信息

Transl Androl Urol. 2017 Apr;6(2):216-221. doi: 10.21037/tau.2016.11.02.

DOI:10.21037/tau.2016.11.02
PMID:28540229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5422699/
Abstract

Penile transplantation is a novel approach to management of penile loss in the developing field of composite tissue allotransplantation (CTA). Prior management for significant penile loss has been free flap phalloplasty with issues related to function, cosmesis, and functional loss from the location of flap harvest. Transplantation has been an evolving field with advancement in CTA over the past several decades leading to the option of penile transplant. Management of penile injury with replantation provided some preliminary groundwork on the technical aspects for penile transplantation. Additionally, penile transplantation raises many ethical, emotional, and psychological considerations with need for patience amidst ongoing advancement within the field.

摘要

阴茎移植是复合组织异体移植(CTA)这一发展领域中治疗阴茎缺失的一种新方法。此前,对于严重阴茎缺失的治疗方法是游离皮瓣阴茎成形术,但存在功能、美观以及因皮瓣切取部位导致的功能丧失等相关问题。在过去几十年里,随着CTA技术的进步,移植领域不断发展,从而出现了阴茎移植这一选择。阴茎再植术对阴茎损伤的治疗为阴茎移植的技术方面提供了一些初步基础。此外,阴茎移植引发了许多伦理、情感和心理方面的考量,在该领域不断发展的过程中需要保持耐心。

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引用本文的文献

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2
Attitudes Toward Penile Transplantation Among Urologists and Health Professionals.泌尿科医生和卫生专业人员对阴茎移植的态度。
Sex Med. 2018 Dec;6(4):316-323. doi: 10.1016/j.esxm.2018.06.003. Epub 2018 Jul 26.

本文引用的文献

1
Genitourinary injuries and extremity amputation in Operations Enduring Freedom and Iraqi Freedom: Early findings from the Trauma Outcomes and Urogenital Health (TOUGH) project.持久自由行动和伊拉克自由行动中的泌尿生殖系统损伤和四肢截肢:创伤结局和泌尿生殖健康 (TOUGH) 项目的早期发现。
J Trauma Acute Care Surg. 2016 Nov;81(5 Suppl 2 Proceedings of the 2015 Military Health System Research Symposium):S95-S99. doi: 10.1097/TA.0000000000001122.
2
Chronic Rejection in Human Vascularized Composite Allotransplantation (Hand and Face Recipients): An Update.慢性排斥反应在人类血管化复合组织同种异体移植(手和面部受者)中的研究进展
Transplantation. 2016 Oct;100(10):2053-61. doi: 10.1097/TP.0000000000001248.
3
Penis Allotransplantation in Beagle Dog.比格犬阴茎异体移植
Biomed Res Int. 2016;2016:1489204. doi: 10.1155/2016/1489204. Epub 2016 Feb 8.
4
World's first successful penis transplant at Tygerberg Hospital.世界首例阴茎移植手术在泰格堡医院取得成功。
S Afr Med J. 2015 Apr;105(4):251-2. doi: 10.7196/samj.9602.
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Acute rejection in vascularized composite allotransplantation.血管化复合组织异体移植中的急性排斥反应。
Curr Opin Organ Transplant. 2014 Dec;19(6):531-44. doi: 10.1097/MOT.0000000000000140.
6
Genital self-amputation or the Klingsor syndrome: Successful non-microsurgical penile replantation.生殖器自断或克林索综合征:非显微外科阴茎再植成功
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Ethical issues in penile transplantation.阴茎移植中的伦理问题。
Asian J Androl. 2010 Nov;12(6):795-800. doi: 10.1038/aja.2010.88. Epub 2010 Sep 13.
9
Penile reconstruction: is the radial forearm flap really the standard technique?阴茎重建:桡侧前臂皮瓣真的是标准技术吗?
Plast Reconstr Surg. 2009 Aug;124(2):510-518. doi: 10.1097/PRS.0b013e3181aeeb06.
10
History of solid organ transplantation and organ donation.实体器官移植与器官捐赠的历史。
Crit Care Clin. 2009 Jan;25(1):165-84, ix. doi: 10.1016/j.ccc.2008.12.001.