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变应性哮喘中的变应原回避

Allergen Avoidance in Allergic Asthma.

作者信息

Cipriani Francesca, Calamelli Elisabetta, Ricci Giampaolo

机构信息

Pediatric Unit, S. Orsola-Malpighi Hospital, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Pediatric and Neonatology Unit, Imola Hospital, Bologna, Italy.

出版信息

Front Pediatr. 2017 May 10;5:103. doi: 10.3389/fped.2017.00103. eCollection 2017.

Abstract

Allergic asthma is the most frequent disease among the chronic respiratory disorders in pediatric age with an important social impact. In the last years, many efforts have been made to identify effective preventive approaches to get a better control of symptoms and to obtain the best future outcomes for the patients. In patients with allergic asthma triggered by the exposure to indoor allergens, the avoidance is the first intervention to prevent the appearance or the worsening of bronchial symptoms. This review article summarized the most recent evidence from literature about the efficacy of specific control interventions for the most important allergens. Even if a wide spectrum of interventions has been suggested and may help to reduce exposure to trigger allergy for sensitized patients suffering from respiratory allergy, evidence supporting the efficacy of these approaches is still weak and subject of controversy. However, the exposure control to specific airborne allergens is still widely recommended and may be effective as part of a holistic approach to reduce the severity of allergic respiratory symptoms in sensitized individuals.

摘要

过敏性哮喘是小儿慢性呼吸道疾病中最常见的疾病,具有重要的社会影响。近年来,人们付出了诸多努力来确定有效的预防方法,以更好地控制症状,并为患者取得最佳的未来预后。在因接触室内过敏原引发过敏性哮喘的患者中,避免接触是预防支气管症状出现或加重的首要干预措施。这篇综述文章总结了文献中关于针对最重要过敏原的特定控制干预措施疗效的最新证据。尽管已经提出了广泛的干预措施,且这些措施可能有助于减少致敏的呼吸道过敏患者接触引发过敏的物质,但支持这些方法疗效的证据仍然薄弱且存在争议。然而,对特定空气传播过敏原的接触控制仍然被广泛推荐,并且作为整体方法的一部分,可能有效地减轻致敏个体过敏性呼吸道症状的严重程度。

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